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1

Drug-induced liver injury

Andrade, Raul J., Chalasani, Naga, Björnsson, Einar S., Suzuki, Ayako, Kullak-Ublick, Gerd A., Watkins, Paul B., Devarbhavi, Harshad, Merz, Michael, Lucena, M. Isabel, Kaplowitz, Neil, Aithal, Gurupra

Journal:

Nature Reviews Disease Primers

Year:

2019

Language:

english

File:

PDF, 1.78 MB

english, 2019

2

Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis — An open pilot study

Biedermann, Luc, Mwinyi, Jessica, Scharl, Michael, Frei, Pascal, Zeitz, Jonas, Kullak-Ublick, Gerd A., Vavricka, Stephan R., Fried, Michael, Weber, Achim, Humpf, Hans-Ulrich, Peschke, Simone, Jetter,

Journal:

Journal of Crohn's and Colitis

Year:

2013

Language:

english

File:

PDF, 712 KB

english, 2013

3

Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Boström, Adrian E., Chatzittofis, Andreas, Ciuculete, Diana-Maria, Flanagan, John N., Krattinger, Regina, Bandstein, Marcus, Mwinyi, Jessica, Kullak-Ublick, Gerd A., Öberg, Katarina Görts, Arver, Stef

Journal:

Year:

2019

Language:

english

File:

PDF, 2.16 MB

english, 2019

4

Phynx: an open source software solution supporting data management and web-based patient-level data review for drug safety studies in the general practice research database and other health care databases

Marco Egbring, Gerd A. Kullak-Ublick, Stefan Russmann

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2010

Language:

english

File:

PDF, 161 KB

english, 2010

5

Transporters involved in the hepatic uptake of 99mTc-mebrofenin and indocyanine green

Wilmar de Graaf, Stephanie Häusler, Michal Heger, Tessa M. van Ginhoven, Gert van Cappellen, Roelof J. Bennink, Gerd A. Kullak-Ublick, Rolf Hesselmann, Thomas M. van Gulik, Bruno Stieger

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 1.34 MB

english, 2011

6

Vitamin D3 transactivates the zinc and manganese transporter SLC30A10 via the Vitamin D receptor

da Silva, Claro, Hiller, Christian, Gai, Zhibo, Kullak-Ublick, Gerd A.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 3.07 MB

english, 2016

7

TNF-α Deficiency Prevents Renal Inflammation and Oxidative Stress in Obese Mice

Wang, Huaiguo, Li, Jian, Gai, Zhibo, Kullak-Ublick, Gerd A., Liu, Zewei

Journal:

Kidney & Blood Pressure Research

Year:

2017

Language:

english

File:

PDF, 2.04 MB

english, 2017

8

Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

Church, Rachel J., Kullak-Ublick, Gerd A., Aubrecht, Jiri, Bonkovsky, Herbert L., Chalasani, Naga, Fontana, Robert J., Goepfert, Jens C., Hackman, Frances, King, Nicholas M. P., Kirby, Simon, Kirby, P

Journal:

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

9

Analysis of Drug-Drug Interactions in Swiss Claims Data Using Tizanidine and Ciprofloxacin as a Prototypical Contraindicated Combination

Jödicke, Annika M., Curkovic, Ivanka, Zellweger, Urs, Tomka, Ivan T., Neuer, Thomas, Kullak-Ublick, Gerd A., Roos, Malgorzata, Egbring, Marco

Journal:

Annals of Pharmacotherapy

Year:

2018

Language:

english

File:

PDF, 205 KB

english, 2018

10

Hypermethylation-associated downregulation of microRNA-4456 in hypersexual disorder with putative influence on oxytocin signalling: A DNA methylation analysis of miRNA genes

Boström, Adrian E., Chatzittofis, Andreas, Ciuculete, Diana-Maria, Flanagan, John N., Krattinger, Regina, Bandstein, Marcus, Mwinyi, Jessica, Kullak-Ublick, Gerd A., Öberg, Katarina Görts, Arver, Stef

Journal:

Year:

2019

File:

PDF, 2.16 MB

2019

11

Functional characterization of the basolateral rat liver organic anion transporting polypeptide

Gerd-Achim Kullak-Ublick, Bruno Hagenbuch, Bruno Stieger, Allan W. Wolkoff, Peter J. Meier

Journal:

Year:

1994

Language:

english

File:

PDF, 717 KB

english, 1994

12

Long-term effects of cholecystectomy on bile acid metabolism

Gerd-Achim Kullak-Ublick, Gustav Paumgartner, Frieder Berr

Journal:

Year:

1995

Language:

english

File:

PDF, 655 KB

english, 1995

13

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis

Christiane Pauli-Magnus, Reinhold Kerb, Karin Fattinger, Thomas Lang, Birgit Anwald, Gerd A. Kullak-Ublick, Ulrich Beuers, Peter J. Meier

Journal:

Year:

2004

Language:

english

File:

PDF, 953 KB

english, 2004

14

Linkage between a new splicing site mutation in the MDR3 alias ABCB4 gene and intrahepatic cholestasis of pregnancy

Gudrun Schneider, Teresa C. Paus, Gerd A. Kullak-Ublick, Peter J. Meier, Thomas F. Wienker, Thomas Lang, Patricia van de Vondel, Tilman Sauerbruch, Christoph Reichel

Journal:

Year:

2007

Language:

english

File:

PDF, 601 KB

english, 2007

15

Pharmacogenetics of drug-induced liver injury

Stefan Russmann, Alexander Jetter, Gerd A. Kullak-Ublick

Journal:

Year:

2010

Language:

english

File:

PDF, 501 KB

english, 2010

16

Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes

Ulrich Beuers, Irmelin Probst, Carol Soroka, James L. Boyer, Gerd-A. Kullak-Ublick, Gustav Paumgartner

Journal:

Year:

1999

Language:

english

File:

PDF, 331 KB

english, 1999

17

Expression of the hepatocyte canalicular multidrug resistance protein (MRP2) in primary biliary cirrhosis

Gerd A Kullak-Ublick, Gustavo B Baretton, Monika Oswald, Eberhard L Renner, Gustav Paumgartner, Ulrich Beuers

Journal:

Hepatology Research

Year:

2002

Language:

english

File:

PDF, 164 KB

english, 2002

18

Successful use of the Molecular Adsorbent Recirculating System (MARS) in a patient with primary biliary cirrhosis (PBC) and treatment refractory pruritus

Beat Mullhaupt, Gerd A. Kullak-Ublick, Patrice M. Ambühl, Reto Stocker, Eberhard L. Renner

Journal:

Hepatology Research

Year:

2003

Language:

english

File:

PDF, 121 KB

english, 2003

19

Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver

Manfred G. Ismair, Carmen Stanca, Huy R. Ha, Eberhard L. Renner, Peter J. Meier, Gerd A. Kullak-Ublick

Journal:

Hepatology Research

Year:

2003

Language:

english

File:

PDF, 270 KB

english, 2003

20

Expression of hepatic transporters OATP-C and MRP2 in primary sclerosing cholangitis

Monika Oswald, Gerd A. Kullak-Ublick, Gustav Paumgartner, Ulrich Beuers

Journal:

Liver International

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

21

Epidemiology of drug exposure and adverse drug reactions in two Swiss departments of internal medicine

Karin Fattinger, Malgorzata Roos, Patrice Vergères, Clemens Holenstein, Brigitt Kind, Urspeter Masche, David N. Stocker, Suzanne Braunschweig, Gerd A. Kullak-Ublick, Renato L. Galeazzi, Ferenc Follath

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 130 KB

english, 2000

22

Tauroursodeoxycholic acid mobilizes α-PKC after uptake in human HepG2 hepatoma cells

Helena Glasova, Thomas M. Berghaus, Gerd A. Kullak-Ublick, Gustav Paumgartner, Ulrich Beuers

Journal:

European Journal of Clinical Investigation

Year:

2002

Language:

english

File:

PDF, 104 KB

english, 2002

23

Drug information for patients—an update of long-term results: type of enquiries and patient characteristics

Martin Huber, Gerd A. Kullak-Ublick, Wilhelm Kirch

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2009

Language:

english

File:

PDF, 127 KB

english, 2009

24

Evaluation of drug interactions and dosing in 484 neurological inpatients using clinical decision support software and an extended operational interaction classification system (Zurich Interaction System)

Markus Guzek, Olesya I. Zorina, Alexander Semmler, Roman R. Gonzenbach, Martin Huber, Gerd A. Kullak-Ublick, Michael Weller, Stefan Russmann

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2011

Language:

english

File:

PDF, 181 KB

english, 2011

25

6 Jahre Erfahrungen mit einem Arzneimittelberatungsdienst für Patienten

Martin Huber, Gerd A. Kullak-Ublick, Wilhelm Kirch

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

2009

Language:

german

File:

PDF, 264 KB

german, 2009

26

Letter to the editor by Drs. Gatti and Bertazzoli entitled “Evaluation of isolated case reports on hepatotoxicity”

Karin Fattinger, Gerd A. Kullak-Ublick

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 48 KB

english, 2002

27

Performance of different data sources in identifying adverse drug events in hospitalized patients

Marco Egbring, Elmira Far, Alexander Knuth, Malgorzata Roos, Wilhelm Kirch, Gerd A. Kullak-Ublick

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 555 KB

english, 2011

28

Evaluation of medication safety in the discharge medication of 509 surgical inpatients using electronic prescription support software and an extended operational interaction classification

Thomas Frölich, Olesya Zorina, Andrea O. Fontana, Gerd A. Kullak-Ublick, Andreas Vollenweider, Stefan Russmann

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 299 KB

english, 2011

29

Fatal hepatotoxicity secondary to nimesulide

Giorgio Merlani, Mark Fox, Hans-Peter Oehen, Gieri Cathomas, Eberhard L. Renner, Karin Fattinger, Markus Schneemann, Gerd A. Kullak-Ublick

Journal:

European Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 257 KB

english, 2001

30

Medical Treatment of Primary Sclerosing Cholangitis: A Role for Novel Bile Acids and other (post-)Transcriptional Modulators?

Ulrich Beuers, Gerd A. Kullak-Ublick, Thomas Pusl, Erik R. Rauws, Christian Rust

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2009

Language:

english

File:

PDF, 309 KB

english, 2009

31

Effect ofABCB1Genotype on Pre- and Post-Cardiac Transplantation Plasma Lipid Concentrations

Anne B. Taegtmeyer, Jane B. Breen, John Smith, Paula Rogers, Gerd A. Kullak-Ublick, Magdi H. Yacoub, Nicholas R. Banner, Paul J. R. Barton

Journal:

Journal of Cardiovascular Translational Research

Year:

2011

Language:

english

File:

PDF, 166 KB

english, 2011

32

Microlithiasis and sludge

Christoph Jüngst, Gerd Achim Kullak-Ublick, Dieter Jüngst

Journal:

Best Practice & Research Clinical Gastroenterology

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

33

Electronic prescribing increases uptake of clinical pharmacologists' recommendations in the hospital setting

Anne B. Taegtmeyer, Ivanka Curkovic, Kaspar Rufibach, Natascia Corti, Edouard Battegay, Gerd A. Kullak-Ublick

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 674 KB

english, 2011

34

Ribavirin/interferon-α sequential treatment of recurrent hepatitis C after liver transplantation

Emiliano Giostra, Gerd A. Kullak-Ublick, Walter Keller, Ronald Fried, Claire Vanlemmens, Stephan Kraehenbuhl, Sandrine Locher, Hans-Peter Egger, Pierre-Alain Clavien, Antoine Hadengue, Gilles Mentha,

Journal:

Transplant International

Year:

2004

Language:

english

File:

PDF, 734 KB

english, 2004

35

Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells

Gerd A. Kullak-Ublick, Manfred G. Ismair, Ralf Kubitz, Marcus Schmitt, Dieter Häussinger, Bruno Stieger, Bruno Hagenbuch, Peter J. Meier, Ulrich Beuers, Gustav Paumgartner

Journal:

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

36

Tumor necrosis factor-α and interferon-γ increase PepT1 expression and activity in the human colon carcinoma cell line Caco-2/bbe and in mouse intestine

Stephan R. Vavricka, Mark W. Musch, Mikihiro Fujiya, Keri Kles, Laura Chang, Jyrki J. Eloranta, Gerd A. Kullak-Ublick, Ken Drabik, Didier Merlin, Eugene B. Chang

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

37

Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C–dependent mechanisms in cholestatic rat liver

Ulrich Beuers, Manfred Bilzer, Anila Chittattu, Gerd A. Kullak-Ublick, Dietrich Keppler, Gustav Paumgartner, Frank Dombrowski

Journal:

Year:

2001

Language:

english

File:

PDF, 384 KB

english, 2001

38

Protein kinase C–dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells

Ralf Kubitz, Clemens Huth, Marcus Schmitt, Axel Horbach, Gerd Kullak-Ublick, Dieter Häussinger

Journal:

Year:

2001

Language:

english

File:

PDF, 735 KB

english, 2001

39

Organic anion transporting polypeptides, cholestasis, and nuclear receptors

Gerd A. Kullak-Ublick, Diana Jung, Bruno Hagenbuch, Peter J. Meier

Journal:

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

40

Hepatocyte nuclear factor 1α: A key mediator of the effect of bile acids on gene expression

Diana Jung, Gerd A. Kullak-Ublick

Journal:

Year:

2003

Language:

english

File:

PDF, 485 KB

english, 2003

41

Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis

Andreas Geier, Christoph G. Dietrich, Sebastian Voigt, Suk-Kyum Kim, Thomas Gerloff, Gerd A. Kullak-Ublick, Johann Lorenzen, Siegfried Matern, Carsten Gartung

Journal:

Year:

2003

Language:

english

File:

PDF, 381 KB

english, 2003

42

Crohn's disease-associated polymorphism within the PTPN2 gene affects muramyl-dipeptide-induced cytokine secretion and autophagy

Michael Scharl, Jessica Mwinyi, Anne Fischbeck, Katharina Leucht, Jyrki J. Eloranta, Joba Arikkat, Theresa Pesch, Silvia Kellermeier, Alma Mair, Gerd A. Kullak-Ublick, Kaspar Truninger, Faiza Noreen,

Journal:

Inflammatory Bowel Diseases

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

43

Comparative evaluation of the drug interaction screening programs MediQ and ID PHARMA CHECK in neurological inpatients

Olesya I. Zorina, Patrick Haueis, Alexander Semmler, Isabelle Marti, Roman R. Gonzenbach, Markus Guzek, Gerd A. Kullak-Ublick, Michael Weller, Stefan Russmann

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2012

Language:

english

File:

PDF, 115 KB

english, 2012

44

Comparative evaluation of three clinical decision support systems: prospective screening for medication errors in 100 medical inpatients

Fritz, Daniela, Ceschi, Alessandro, Curkovic, Ivanka, Huber, Martin, Egbring, Marco, Kullak-Ublick, Gerd A., Russmann, Stefan

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

45

Oral heroin in opioid-dependent patients: Pharmacokinetic comparison of immediate and extended release tablets

Ludwig Perger, Katharina M. Rentsch, Gerd A. Kullak-Ublick, Davide Verotta, Karin Fattinger

Journal:

European Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

46

Deoxycholic acid is not related to lithogenic factors in gallbladder bile

Dieter Jüngst, Iris Müller, Gerd Achim Kullak-Ublick, Günther Meyer, Eckart Frimberger, Sven Fischer

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1999

Language:

english

File:

PDF, 794 KB

english, 1999

47

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

Jyrki J. Eloranta, Gerd A. Kullak-Ublick

Journal:

Archives of Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 681 KB

english, 2005

48

Mushroom poisoning: A study on circumstances of exposure and patterns of toxicity

Katharina M. Schenk-Jaeger, Christine Rauber-Lüthy, Michael Bodmer, Hugo Kupferschmidt, Gerd A. Kullak-Ublick, Alessandro Ceschi

Journal:

European Journal of Internal Medicine

Year:

2012

Language:

english

File:

PDF, 250 KB

english, 2012

49

The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3β in hepatocellular carcinoma

Stephan R Vavricka, Diana Jung, Michael Fried, Uwe Grützner, Peter J Meier, Gerd A Kullak-Ublick

Journal:

Journal of Hepatology

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

50

Enterohepatic transport of bile salts and genetics of cholestasis

Christiane Pauli-Magnus, Bruno Stieger, Yvonne Meier, Gerd A. Kullak-Ublick, Peter J. Meier

Journal:

Journal of Hepatology

Year:

2005

Language:

english

File:

PDF, 278 KB

english, 2005